419 research outputs found
Application of a new screening model to thermonuclear reactions of the rp process
A new screening model for astrophysical thermonuclear reactions was derived
recently which improved Salpeter's weak-screening one. In the present work we
prove that the new model can also give very reliable screening enhancement
factors (SEFs) when applied to the rp process. According to the results of the
new model, which agree well with Mitler's SEFs, the screened rp reaction rates
can be, at most, twice as fast as the unscreened ones.Comment: 8 RevTex pages + 7 ps figures. (Revised version). Accepted for
publication in Journal of Physics
Screened alpha decay in dense astrophysical plasmas and magnetars
This paper shows that ultrastrong magnetic fields (such as those of
magnetars) and dense astrophysical plasmas can reduce the half life of alpha
decaying nuclei by many orders of magnitude. In such environments the
conventional Geiger-Nuttall law is modifed so that all half lives are shifted
to dramatically lower values. Those effects, which have never been investigated
before, may have significant implications on the universal abundances of heavy
radioactive elements and the cosmochronological methods that rely on them.Comment: 15 RevTex pages, 3 ps figures (minor revision). This work was
presented during the conference ''Supernova, 10 years of SN1993J'', April
2003, Valencia, Spain. Accepted for publication in Phys.Rev.
Astrophysical factors:Zero energy vs. Most effective energy
Effective astrophysical factors for non-resonant astrophysical nuclear
reaction are invariably calculated with respect to a zero energy limit. In the
present work that limit is shown to be very disadvantageous compared to the
more natural effective energy limit. The latter is used in order to modify the
thermonuclear reaction rate formula so that it takes into account both plasma
and laboratory screening effects.Comment: 7 RevTex pages. Accepted for publication in Phys.Rev.
Atomic effects in astrophysical nuclear reactions
Two models are presented for the description of the electron screening
effects that appear in laboratory nuclear reactions at astrophysical energies.
The two-electron screening energy of the first model agrees very well with the
recent LUNA experimental result for the break-up reaction , which so far defies all available theoretical models.
Moreover, multi-electron effects that enhance laboratory reactions of the CNO
cycle and other advanced nuclear burning stages, are also studied by means of
the Thomas-Fermi model, deriving analytical formulae that establish a lower and
upper limit for the associated screening energy. The results of the second
model, which show a very satisfactory compatibility with the adiabatic
approximation ones, are expected to be particularly useful in future
experiments for a more accurate determination of the CNO astrophysical factors.Comment: 14 RevTex pages + 2 ps (revised) figures. Phys.Rev.C (in production
Screened thermonuclear reactions and predictive stellar evolution of detached double-lined eclipsing binaries
The low energy fusion cross sections of charged-particle nuclear reactions
(and the respective reaction rates) in stellar plasmas are enhanced due to
plasma screening effects. We study the impact of those effects on predictive
stellar evolution simulations for detached double-lined eclipsing binaries. We
follow the evolution of binary systems (pre-main sequence or main sequence
stars) with precisely determined radii and masses from 1.1Mo to 23Mo (from
their birth until their present state). The results indicate that all the
discrepancies between the screened and unscreened models (in terms of
luminosity, stellar radius, and effective temperature) are within the
observational uncertainties. Moreover, no nucleosynthetic or compositional
variation was found due to screening corrections. Therefore all thermonuclear
screening effects on the charged-particle nuclear reactions that occur in the
binary stars considered in this work (from their birth until their present
state) can be totally disregarded. In other words, all relevant
charged-particle nuclear reactions can be safely assumed to take place in a
vacuum, thus simplifying and accelerating the simulation processes.Comment: 5 RevTex pages,no figures. Accepted for publication in Phys.Rev.
Screening enhancement factors for laboratory CNO and rp astrophysical reactions
Cross sections of laboratory CNO and rp astrophysical reactions are enhanced
due to the presence of the multi-electron cloud that surrounds the target
nuclei. As a result the relevant astrophysical factors are overestimated unless
corrected appropriately. This study gives both an estimate of the error
committed if screening effects are not taken into account and a rough profile
of the laboratory energy thresholds at which the screening effect appears. The
results indicate that, for most practical purposes, screening corrections to
past relevant experiments can be disregarded. Regarding future experiments,
however, screening corrections to the CNO reactions will certainly be of
importance as they are closely related to the solar neutrino fluxes and the rp
process. Moreover, according to the present results, screening effects will
have to be taken into account particularly by the current and future LUNA
experiments, where screened astrophysical factors will be enhanced to a
significant degree.Comment: 6 RevTex pages + 2 ps figures. (Revised version). Accepted for
publication in Journal of Physics
The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata
The Genomes OnLine Database (GOLD, http://www.genomesonline.org/) is a comprehensive resource for centralized monitoring of genome and metagenome projects worldwide. Both complete and ongoing projects, along with their associated metadata, can be accessed in GOLD through precomputed tables and a search page. As of September 2011, GOLD, now on version 4.0, contains information for 11â472 sequencing projects, of which 2907 have been completed and their sequence data has been deposited in a public repository. Out of these complete projects, 1918 are finished and 989 are permanent drafts. Moreover, GOLD contains information for 340 metagenome studies associated with 1927 metagenome samples. GOLD continues to expand, moving toward the goal of providing the most comprehensive repository of metadata information related to the projects and their organisms/environments in accordance with the Minimum Information about any (x) Sequence specification and beyond
Radiolabeled iron oxide nanoparticles functionalized with PSMA/BN ligands for dual-targeting of prostate cancer
IntroductionProstate cancer (PCa) is the second most frequent cancer diagnosis in men and the fifth leading cause of death worldwide. Prostate Specific Membrane Antigen (PSMA) and Gastrin Releasing Peptide (GRP) receptors are overexpressed in PCa. In this study, we have developed iron oxide nanoparticles (IONs) functionalized with the Prostate Specific Membrane Antigen (PSMA) and Gastrin Releasing Peptide (GRP) ligands for dual targeting of Prostate cancer.MethodsIONs were developed with a thin silica layer on their surface with MPTES (carrying -SH groups, IONs-SH), and they were coupled either with a pharmacophore targeting PSMA (IONs-PSMA) or with bombesin peptide (IONs-BN), targeting GRP receptors, or with both (IONs-PSMA/BN). The functionalized IONs were characterized for their size, zeta potential, and efficiency of functionalization using dynamic light scattering (DLS) and Fourier-Transform Infrared Spectroscopy (FT-IR). All the aforementioned types of IONs were radiolabeled directly with Technetium-99m (99mTc) and evaluated for their radiolabeling efficiency, stability, and binding ability on two different PCa cell lines (PC3 and LNCaP).Results and DiscussionThe MTT assay demonstrated low toxicity of the IONs against PC3 and LNCaP cells, while the performed wound-healing assay further proved that these nanostructures did not affect cellular growth mechanisms. The observed hemolysis ratio after co-incubation with red blood cells was extremely low. Furthermore, the 99mTc-radiolabeled IONs showed good stability in human serum, DTPA, and histidine, and high specific binding rates in cancer cells, supporting their future utilization as potential diagnostic tools for PCa with Single Photon Emission Computed Tomography (SPECT) imaging
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